Endocannabinoids & Phytocannabinoids
Research into the Endocannabinoid System (ECS) appears to have hit a complete standstill, especially in Britain. All of the information available about the ECS in Britain is now completely obsolete, the NHS Scotland opted to stop posting their results in 2014 and they claim that our bodies only have two receptors, CB1 and CB2 and that using THC will induce psychotic symptoms in healthy individuals. This is not at all accurate, failing to understand how this system works as a whole can have some seriously negative impacts on your health when misusing certain products. We will cover all of this very shortly, first we would like to give you a more accurate introduction to the ECS.
The endogenous cannabinoid system was first described in 1988 and has been studied using genetic and pharmacological methods. These and more recent studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. In 1992 endogenous ligands of the cannabinoid system were discovered for the first time, one of which is anandamide which is a released during exercise and is responsible for the exercise induced altered state of consciousness known as “runners high” that has long been appreciated by endurance athletes.
Your body produces ENDOCannabinoids.
Plants produce PHYTOCannabinoids.
ENDO translates to “internal” or “within”.
PHYTO translates to “of a plant” or “relating to plants”.
Anandamide is an Endocannabinoid, the body’s own version of cannabis, scientists have found that after 30 minutes of exercise anandamide levels increase and found that feelings of wellbeing in patients was tightly correlated to levels of anandamide in their bloodstream.THC’s chemical structure is similar to anandamide. Similarity in structure allows the body to recognise THC and to alter normal brain communication. If THC was never discovered, anandamide might never have been discovered. THC fits perfectly into the special receptors in the brain and central nervous system.Scientists describe Endocannabinoids receptors as locks and the cannabinoid molecules that bind with them are described as keys. Essentially, they fit like “lock and key”. The Ligands that bind and activate these receptors include light sensitive ligands, odours, pheromones, hormones and neurotransmitters. These G Protein-Coupled receptors are involved in virtually all diseases and are also the target of approximately 34% of all modern day medicinal drugs.